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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395c3bb844253149ba1602957cdbc6afe38f4ff575ca0f8ffc2d157434f215a0' 
  AND token = 'wcl+rcFois4kPZP6zV3SI4IbJFrPNAM/sHoVG6RYy4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}