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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7732fd80022b295a289e4b4be5f80a3e0de44c809e1aa99037ef9f66fcad9a01' 
  AND token = 'gxdIuYQx94e4BV0h8PwO7W3RFTNrg28eObVtEZ2R0js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}