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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d574437f263766636d0337a2087a723a213ffe49ccb4dad0ce57b947ee3dc5' 
  AND token = 'I/Yqt2EWZJ7SbP30n9KzS/85PpiVdVY434hvkpDjzYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}