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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e6c006580c9dcf6a10cab7d3ad8f65221feb6e438a81e103f80febde0991a5' 
  AND token = 'PDQp1MQqHFglTx60I+oDkIGLaOLmJipz07Sjq82IedA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}