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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2982f8ca09a29d3be3d087b1a47011d1e501f032d1d983ddd149a95b8ca6d5' 
  AND token = 'RGY3uscDXSD6NE/PWRa8+JJ1XBs+KLqzztfiSwrdtpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}