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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162ad5c7b1928f14e938cfcb848360805f350ef927e1ff45545bbe4b78aaf7ae' 
  AND token = 'LQSfaFQMS5CI2KPFRdRCMr+PW63lNn1ijBjwHkCmzhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}