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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6549920716ad8c0f27c7562ebc28ded163c40a50a14a329c17de109a12621672' 
  AND token = '2KI61+18UYMQ1K0nSbwk8jUmwwJtTkCYdhpnnH37UbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}