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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb46c4733ecbac4c39a93cfc6bf2d5ee3d7d792faead94a03dd222176d5afd0' 
  AND token = '5JicKw1AcxyJwpAGyIBUg3UOeAsEp8YOsW74jxqu/0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}