SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9134f6266d49b4d40de441e0671434d0400397240ecb1eaf7240e4a20640857' 
  AND token = 'yDK4N6mmDPbcooJZyAABYVlkExLIpyqk9FZ5F2EBJbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}