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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e73da8ea230ac253b49f4935c4ab571346a09147db1ffc5c5fe71d9241715ca0' 
  AND token = 'xUwF+lcq10qow2S0rAwv2vuZa0AMwepANlHxztLgOeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}