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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da756681f80e9a063a97635c70bd871a091dd1cb763236b4b50354441e21db65' 
  AND token = '9QrA50dSRgdjHryTYS7MjcNWfmo8CC5ZiM18Mt24Ad8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}