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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecffc06d449d4e1a3921765d20a6f19e484ddc4766bbc3bf637c027c7c4b380f' 
  AND token = 'WFQQPEOAYlMEB11put9W1hEjMWB2SHuh7XC4Lqi51vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}