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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3feb9bd65a5fc3658516343e7120dc3b148c462a9f1aa5f7be989a99db45da03' 
  AND token = 'NIuENmaG9M24pTXp3HBTZ3yJYrtTBZphiUSi1xjL73k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}