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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86e50ba44cdbc207d4984cd4ca3ce2ac41a27ee63a9a36e590f168c2daa4ca76' 
  AND token = 'hXcItFXza1c3pF2wu1ux+v8wgmCN3YhXL2XRSPY3eQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}