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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7582956d097e8641f97ed26a8a023a16b48c827200d0243ccef9dd20248ac2' 
  AND token = '7XixO3UM2A094vMZq3SWPcBietLZ5NWvFxwNChSyhOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}