SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c17018f51bf4bb570728768275d599bf1c46e36632a8a996d09f4201fe2c4ffe' 
  AND token = 'EM5TUfoVRgMo3oznjCa0LOR3didNGMrKEOxVL62uy+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}