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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f34e6c8265b9e909bc8fed8e3c35f41a94153c65f9cc681b4ed9165811d6847' 
  AND token = 'JBMrIbyda8aR3QX366bK9V2AZOIdJULybOMkQsRcfAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}