SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b6e6ddffac7b15e3ca624826edc79942ef14b1383952d7ae3680ab37ab1f5e' 
  AND token = 'X6qsGkuzhnmMsQdTT+bU67jU9HMaikXXigbXx/eEgGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}