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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46224db08eedd367a9da8533cd7e948b9f8beeed963b60aad25f82e729c49a64' 
  AND token = 'oRyOYYTlc0ALfMOa2PqoxPKJyuX4lZwUm1ypBzSM6OU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}