SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd9a101026d251a72af4f40edf7a85dcdd0d7841e5a3b0c0412f7ac754ae264' 
  AND token = 'iVZJdT5donFtBLX0KLvb9YMfwThzZzAm+00fmCql9Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}