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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c32cfbbb4ab037c8810c4291cbd6cbab2d82497e7bfb65fea49828429e35e1' 
  AND token = 'U5lwrpSD20VtMP59JZbZM/076zW5uRM7kcPlh757uMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}