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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a14388700f88d05773e500347c9ed42ec7a497d7d47b7648ae0368ecd798bb6' 
  AND token = 'L+ADa3+260MJ3yW2tO6GH9P6+RDRWlto26gEr098hn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}