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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388f46b9fe3ce33949bfd8445b69586bba91724b6a04ab4e00fede4245b3303a' 
  AND token = 'mbBboSp6z1KCXg2gg0yy2TK34FJoMlkab/us0nZDBkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}