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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd5210a001a3aa63a7e3d50533f6f623c99e5d915cad592a2f8458b688a180a1' 
  AND token = 'IDXJhkuQn9Mq4y3dM2Rw3Qyd0jKWzmNwyot7ddBREoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}