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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4676719225b780f749532b8c9f03fa7ef3e6d528350761dd12271eca4f37046d' 
  AND token = 'FeOEM5C7iT0FTEu7uEM08KtZb0FNGVI0vW0CyG5MvOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}