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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d56cd61dc19c44fec428bafd69c8f390484363bcbab8b3ddd76aff77d779f2' 
  AND token = 'ZvCKI8fk+cJDD6LEPcO0I5nOTdj5WFavDGdfXC9uEOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}