SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0bfda318142a3d81a435f7850ac4f2cf50486d03849045440a7f49b90e8954' 
  AND token = 'n4SCRAbvO7tBrHoFHUXkoZUkLNAQ/9ZS74R/V09ijTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}