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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f308253e2e9de2f4783f9a25a33f0147c501d3f9d8a4bac8bd388be50843f355' 
  AND token = 'oeARyN8vcQkU+f2lkiEY+mcDUfv8bGplBFUTAEZUjhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}