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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e6911d61b1d942228682ae7249505cbb07c4e4545f7be45b1195ba17dc160a' 
  AND token = 'G4RVofN3mic4HwLMyTSrom68QOEyUHKlgDEVwlaEJaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}