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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea2c22c3dcfbcb755a992c91ed0ffee51e7e16e230b5bb039cfc61d7008b0014' 
  AND token = 'jhrRP3J7lKnk9p/P1XN6t2jDB+zL+S/5Oo2F8nFqtHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}