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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd49aa5b79f9b49aa4ef85a44239fd2b66b0a5704d2be2a0c79eaadeedf7ca81' 
  AND token = '+pqVWYf8BTbr/ehTYF1PkC5guiWAAWyDC2R5VqEzOP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}