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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ae74301a0d19a0a0f384a27afe3e0ef90380f6237dbb8eab9f749c6c66ca1e' 
  AND token = 'H1A/FWIG3gSXAbGV21jtUQH50uCg4GevN7ya0+hTNIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}