SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66ea02af1a7a9c16bc30ed18256e45498433d40aacc75a9270dad3ebbc6c9f6' 
  AND token = 'j1b2eosQD2fqmV4SQw1EijyE639DtMt5QlVE086DOwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}