SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1eedc38a768775330dba0d44bc2524873ef53e69cd12f10712e20b160ce1e07' 
  AND token = 'EW8apHMvP/Om6CHu0XoIjzIYbg9sj2bmoytaW2QvI8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}