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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4d5f0006ea3d0c78a25e415da75a00ad620e20265ecd57e5435df4221dc7c2' 
  AND token = 'NyCCCJurMiURgmA1FrkcRYxwqsQBJ9QoqQW71HdDh1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}