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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5671adb11d3663c1529dd8c1a127babc023cb7395f5fda022d94a73f9417c6c1' 
  AND token = 'ESsTaIPLLwKb0Pdso63J+lEcOqpp+Csd/zf+ewwP+FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}