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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d582b0b04991f2821365b9489caf4afcd2a1d4a5eb240fa0e3b6bd27042b01c' 
  AND token = 'Rq/Q6RBarEs1TRr4/YZL8m+/zE27uqyiU8CfzSDqoRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}