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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd254b54d4acf969a451a797979f8d01add24f41f9339796c81ca3f9b0f266e6d' 
  AND token = '4Rt3G6vNj4b6faz5KzbBiC4vpvgSi3EDPSkuk4RkTDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}