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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2957d192330bea1095be54c760a546944c07e26af895b18120c92ee022024b1' 
  AND token = '0OoMb/SbegaA5GvlwqzhRbUEpgW02r9bcS+5ndmbke8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}