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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4125bdeede7c6af60fbcee45297349d894eb3ee0c0d240bd094f7f6d10d6fe1e' 
  AND token = '4cBP94bv5q8Oq4ZdwfYYcqzSujQFMciZGEl5K6E6dmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}