SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6580f8e2a2378b9cc8736f2c56b970201f3de373d05bc43044071971336e183' 
  AND token = 'JgXpKmbAdXj7SPWgrZ954b35tvYA8zkoqHVzr9Jl3SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}