SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e753a7b544b2b5e13d9cc84436c32a70e719da084d9a7f0f3de78590e2d1421' 
  AND token = '0DKFmbOVPcb8Fh7H8tpGSJO3OGhqfse7UMrlOVyt2io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}