SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36d8acaa4696a3e723714f216ca7f9373c3faa590b53e4db9694ade293116527' 
  AND token = 'c5q3Z3ayKxHVD4ZIEWhqY3goz4XqsR/cKnXgVIO31YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}