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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6bbecd5bb5ec0bcd2cf95ad566924bd5035dcc815123b7b403400eb97aa257a' 
  AND token = 'gzEt5znD5EVCKY2TM1eFIqlLIKGT5mI5CvrfxW3x8qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}