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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f6727cc8609fbe21ced1c2c1dc23ad45e52b0a1cac9621d02ca2060fbbb1ca' 
  AND token = 'kcBhMEc8KyUXR7mCJ1rBdgVg01pCAgnrXCtDM+R2cxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}