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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '30e491f49bae93ada18d7cc41c063daf092dd7f4d4b6f9db05644f0dba723bdf' 
  AND token = 'G8Ei9AlH69Zr3SHBvTA6JFTpcGurmOdPfhQ5Li76+3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}