SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55503957ec4f6819e28d933a3ddf417edad799bffc8c8dd353292a11ed4eefcb' 
  AND token = '74aKH38+ALvW4JfsPs72vQ121XiDzfiSxzmjC2vbvDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}