SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd88f5887b02cce2d20e21a10af3a960197dd2d152475c983b83836c34de2116' 
  AND token = 'whzrw/HrI6qDEyXCbJwqUVwW3j0s1i/39RalQ1c4ewg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}