SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9391d0596bdf9439e10e28e71cf343123fe49cef7e0a8cb33df6debebb7ead91' 
  AND token = 'mHqxPE/DBR43a9rNMyvQulH/1YvcNs+DtQALX3X0DMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}