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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b846196a9ba368b2678b76a32264ca49977d5f39a87f6b60faf1ffec7fbb1a7f' 
  AND token = 'OQ+lbaETrvogoLLhK40s6bzj8MfRILHJDYePmeVAWPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}